Adipokines Involved in Macrophage Recruitment
نویسندگان
چکیده
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نقش آدیپوکینها در پاتوفیزیولوژی بیماریهای قلبی-عروقی
Background: Cardiovascular Diseases (CVDs) are major causes of mortality worldwide. Obesity is regarded as an independent CVDs risk factor. In this article we focus on the role of adipokines which are involved in CVDs pathogenesis. Methods: The recent studies regarding the role of adipokines such as Leptin, Resistin, TNF-α, IL-6, MCP-1, Visfatin, Chemerin, Apelin, Omentin, Adipon...
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OBJECTIVES Adipose tissue from patients with HIV-related lipodystrophy presents a state of chronic inflammation. Altered expression of cytokines/adipokines and macrophage infiltration could be involved in patients' insulin resistance and lipoatrophy. We tested whether antiretrovirals affected adipokine release by human subcutaneous adipocytes and cytokine/chemokine production by human macrophag...
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Background. Assessment of white adipose tissue has changed in recent years, with WAT now being considered as an active endocrine organ, secreting a large number of bioactive mediators, so-called adipokines. Besides other functions, these adipokines are involved in inflammatory response thereby exhibiting predominantly proinflammatory or anti-inflammatory properties and contribute to insulin res...
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تاریخ انتشار 2017